Background:

GCTs are rare but often curable disease even in the presence of metastatic disease. About 50% are pure seminoma. Presentation is with stage I disease in 80% of seminoma and 60% of non-seminoma (Horwich Lancet 2006). Surveillance is offered for stage I disease in Australia in 33% of seminoma, and 73% of non-seminoma (Grimison BJUI 2013).

Objectives:

To determine the proportion of male patients with GCTs at large tertiary referral centre in Sydney presenting with seminoma or non-seminoma and by stage. To determine initial treatment and relapse rates.

Methods:

Males aged ≥ 18 years presenting to Royal Prince Alfred Hospital with a new diagnosis of GCT between January 2009 and March 2013 were identified. Histology, stage, initial treatment, and any relapse were obtained.

Results:

118 eligible patients were identified. Median age was 32 years (15 to 71). Pure seminoma was identified in 59 of 118 (50%). Presentation was with stage I disease in: seminoma  43 of 59 (73%); non-seminoma: 31 of 59 (53%). Median follow-up is 29 months (range 2 to 50). Data is presented below:

Conclusions:

Proportions with seminoma and stage I disease were similar to the literature. Proportions offered surveillance was significantly higher than typical for Australia. Relapse rates were low, but follow-up is relatively short.